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Desert hedgehog promotes ischemia-induced angiogenesis by ensuring peripheral nerve survival. Abstract RATIONALE: Blood vessel growth and patterning have been shown to be regulated by nerve-derived signals. Desert hedgehog (Dhh), one of the Hedgehog family members, is...
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sFRP-1 Improves Postinfarction Scar Formation Through a Modulation of Inflammatory Response. Arterioscler Thromb Vasc Biol. OBJECTIVE: The inflammatory response after myocardial infarction plays a crucial role in the healing process. Lately, there is accumulating...
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Frizzled 4 regulates arterial network organization through noncanonical Wnt/planar cell polarity signaling. Abstract RATIONALE: A growing body of evidence supports the hypothesis that the Wnt/planar cell polarity (PCP) pathway regulates endothelial cell proliferation...
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GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways. AIMS: Ischaemic preconditioning (IPC) protects the heart against prolonged lethal ischaemia through a signalling cascade involving Akt, glycogen synthase...
